Thursday, September 23, 2010

What is max molecular cargo of the substance which can miss through glomeruli of kidney?

plz name the substances also....as tons u can.....What is max molecular cargo of the substance which can miss through glomeruli of kidney?
Molecules larger than 70,000 daltons are not filtered through the glomerulus.
adjectives substance found in the blood outdo through the glomeruli of the kidney except: red blood cells and proteins - the limiting factor is the molecular shape (hence the size) and not the molecular immensity.
But in disease states such as hematuria and proteinuria, even the BIG substances exceed through the glomeruli (see renal failure)
each filtration slit diaphragm delimit a pore of 40 x 140 angstroms, Albumin = 36 angstroms

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